Antibodies are incredibly versatile tools that can be used for many applications including detecting, quantifying, delivering cargos (e.g. small drugs), blocking, or activating specific protein interactions. For this reason, Custom antibody production is an important step in bringing a research project to fruition.
Antibody production can be done either in vivo or in vitro. In vivo production involves injecting an antigen into lab animals such as rabbits, guinea pigs, goats, chickens, and mice in order to obtain high titer antibodies that are highly specific to the target antigen. This process typically takes several months whereas in vitro methods can produce a monoclonal antibody (mAb) within a few weeks.
Custom Antibody Production: Advancing Scientific Discoveries
Once the antibodies are produced they undergo quality control to ensure that the antibodies have a high level of specificity and affinity. Functional assays such as neutralization tests and flow cytometry are also conducted to evaluate the performance of the antibodies in biological contexts. This is crucial to ensuring that the antibodies will work as expected in your particular application.